Starting your own NG-MAST study?
The NG-MAST website provides the official assignment of the
allele numbers for por and tbpB sequences
and assigns official ST numbers to each unique two-digit allelic
profile (see further information).
The site also provides the official list of all known
STs and their two-digit allelic profiles, but it does not
provide a
strain database.
We do, however, provide a facility for those
who wish to maintain their own strain databases - e.g. to
study the strains of N. gonorrhoeae circulating in their
local region
and to allow clusters of identical isolates to be recognised.
Additionally, we can provide groups of laboratories who wish
to share their NG-MAST typing data the option of maintaining
their own private databases, but to give permission to their
collaborators to see and jointly analyse their strain data.
In all cases these private strain databases link to the official
depository of alleles and STs at this website, so that official
assignments of new alleles and STs of strains within the
private databases can be made.
New features will soon be
introduced
for those wishing to use a private strain database to facilitate
the recognition of clusters of indistinguishable gonococcal
isolates within user-defined time frames and to evaluate
their statistical significance based on the allele frequencies
within
the local database.
Please contact David
Aanensen for further
details.